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Sempionatto Research Group
Biosensors and Wearable Platforms
 

Publications

  1. Xu*, Y. Song*, J. R. Sempionatto*, S. A. Solomon, Y. Yu, H.Y. Y. Nyein, R. Y. Tay, J. Li, A. Lao, T. K. Hsiai, J. A. Sumner, Wei Gao, An intelligent physicochemical sensing electronic skin for stress assessment, Nature Electronics, (2023)
  2. Xu, Y., DelaPaz, E., Paul, A., Mahato, K., Sempionatto, J.R., Tostado, N., Lee, M., Hota, G., Lin, M., Uppal, A., Chen, W., Dua, S., Yin, L., Wuerstle, B.L., Deiss, S., Mercier, P., Xu, S., Wang, J., Cauwenberghs, G., In-ear integrated sensor array for the continuous monitoring of brain activity and of lactate in sweat. Nature Biomedical Engineering, 2023
  3. Ye, M. Wang, J. Min, R. Y. Tay, H. Lukas, J. R. Sempionatto, J. Li, C. Xu, W. Gao, A wearable aptamer nanobiosensor for non-invasive female hormone monitoring, Nature Nanotechnology, 2023, 10.1038/s41565-023-01513-0.
  4. Brasier, H. Ceren Ates, J. R. Sempionatto, M. O. Cotta, A. F. Widmer, J. Eckstein, J. Goldhahn, J. A. Roberts, Wei Gao, C. Dincer, A three-level model for therapeutic drug monitoring of antimicrobials at the site of infection, The Lancet Infectious Diseases, (2023), 10.1016/S1473-3099(23)00215-3
  5. Min, S. Demchyshyn, J. R. Sempionatto, Y. Song, B. Hailegnaw, C. Xu, Y. Yang, S. Solomon, C. Putz, L. Lehner, J. F. Schwarz, C. Schwarzinger, M. Scharber, M. Kaltenbrunner, W. Gao*, An autonomous wearable biosensor powered by a perovskite solar cell, Nature Electronics, (2023), 10.1038/s41928-023-00996-y.
  6. R. Sempionatto, J. A. Lasalde-Ramírez, K. Mahato, J. Wang, W. Gao, Wearable chemical sensors for biomarker discovery in the omics era, Nature Reviews Chemistry, (2022), 10.1038/s41570-022-00439-w
  7. Teymourian, F. Tehrani, K. Longardner, K. Mahato, T. Podhajny, J.-M. Moon, Y. G. Kotagiri, J. R. Sempionatto, I. Litvan, and J. Wang. “Closing the loop for patients with Parkinson disease: where are we?” Nature Reviews Neurology (2022) 18, 497-507, https://doi.org/10.1038/s41582-022-00674-1
  8. Yin, L., Cao, M., Kim, K.N., Lin, M., Moon, J.M., Sempionatto, J.R., Yu, J., Liu, R., Wicker, C., Trifonov, A. and Zhang, F., 2022. A stretchable epidermal sweat sensing platform with an integrated printed battery and electrochromic display. Nature Electronics (2022),10,694-705.
  9. Bolat, G., De la Paz, E., Azeredo, N.F., Kartolo, M., Kim, J., de Loyola e Silva, A.N., Rueda, R., Brown, C., Angnes, L., Wang, J. & Sempionatto, J.R., 2022. “Wearable soft electrochemical microfluidic device integrated with iontophoresis for sweat biosensing”. Analytical and Bioanalytical Chemistry (2022), 414(18), 5411-5421.
  10. Sempionatto,R., M. Lin, L. Yin, E. de la Paz, K. Pei, T Sonsa-ard, A. N. de Loyola Silva, A. A. Khorshed, F. Zhang, N. Tostado, S. Xu & J. Wang. An epidermal patch for the simultaneous monitoring of haemodynamic and metabolic biomarkers. Nature Biomedical Engineering, (2021) https://doi.org/10.1038/s41551-021-00685-1
  11. Yin J.M. Moon, J. R. Sempionatto*, M. Lin, M. Cao A. Trifonov, F. Zhang, Z. Lou, J.- M. Jeong, S. J. Lee, S. Xu, J. Wang. A passive perspiration biofuel cell: High energy return on investment. Joule (2021) https://doi.10.1016/j.joule.2021.06.004
  12. Tang, L. Yin,  J. R. Sempionatto*, J.M. Moon,    H. Teymourian, J. Wang Touch‐Based Stressless Cortisol Sensing. Advanced Materials, (2021). https://doi.org/10.1002/adma.202008465
  13. Moon, H.Teymourian, E. De la Paz, J. R. Sempionatto*, K. Mahato, T. Sonsa-ard, N. Huang, K. Longardner, I. Litvan, J. Wang. Non-invasive Sweat-based Tracking of L-Dopa Pharmacokinetic Profiles Following an Oral Tablet Administration. Angewandte Chemie, 133(2021)1 https://doi.org/10.1002/anie.202106674
  14. Min, J.R. Sempionatto*, H. Teymourian, J. Wang and W. Gao Wearable Electrochemical Biosensors in North America. Biosensors and Bioelectronics, 172(2021)112750. https://doi.org/10.1016/j.bios.2020.112750
  15. R. Sempionatto, V. Ruiz-Valdepenas Montiel, E. Vargas, H. Teymourian, J. Wang. Wearable and Mobile Sensors for Personalized Nutrition. ACS Sensors, 6 (2021) 1745. https://doi.org/10.1021/acssensors.1c00553
  16. R. Sempionatto, J. Moon, and J. Wang. “Touch-Based Fingertip Blood-Free Reliable Glucose Monitoring: Personalized Data Processing for Predicting Blood Glucose Concentrations”. ACS Sensors, 61 (2021) 1875.
  17. Montiel, Víctor Ruiz-Valdepeñas, Juliane R. Sempionatto*, Eva Vargas, Eileen Bailey, Jennifer May, Andrea Bulbarello, André Düsterloh, Nathan Matusheski, and Joseph Wang. “Decentralized vitamin C & D dual biosensor chip: Toward personalized immune system support.” Biosensors and Bioelectronics 194 (2021): 113590. https://doi.org/10.1016/j.bios.2021.113590
  18. Barros Azeredo, Nathália Florência, Mauro S. Ferreira Santos, Juliane R. Sempionatto, Joseph Wang, and Lúcio Angnes. “Screen-printed technologies combined with flow analysis techniques: moving from benchtop to everywhere.” Analytical Chemistry (2021): 250-268. https://doi.org/10.1021/acs.analchem.1c02637
  19. Moon, Jong‐Min, Hazhir Teymourian, Ernesto De la Paz, Juliane R. Sempionatto, Kuldeep Mahato, Thitaporn Sonsa‐ard, Nickey Huang, Katherine Longardner, Irene Litvan, and Joseph Wang. “Non‐Invasive Sweat‐Based Tracking of L‐Dopa Pharmacokinetic Profiles Following an Oral Tablet Administration.” Angewandte Chemie International Edition, 35 (2021): 19074-19078. https://doi.org/10.1002/anie.202106674
  20. Teymourian, M. M. Parrilla, J.R. Sempionatto*, N. Montiel, A. Barfidokht, Van R. Echelpoel, K. De Wael, J. Wang Wearable Electrochemical Sensors for the Monitoring and Screening of Drugs. ACS Sensors, 5(2020)2679. https://doi.org/10.1021/acssensors.0c01318
  21. Sempionatto, J. R.; Khorshed, A. A.; Ahmed, A.; Loyola, A. N. De; Barfidokht, A.; Yin, L.; Goud, K. Y.; Mohamed, M. A.; Bailey, E.; Aebischer, C.; et al. Epidermal Enzymatic Biosensor for Sweat Vitamin C : Towards Personalized Nutrition. ACS Sensors 2020, acssensors.0c00604. https://doi.org/10.1021/acssensors.0c00604
  22. Sempionatto, J. R.; Raymundo-Pereira, P. A.; B. Azeredo, N. F.; N. De Loyola e Silva, A.; Angnes, L.; Wang, J. Enzymatic Biofuel Cells Based on Protective Hydrophobic Carbon Paste Electrodes: Towards Epidermal Bioenergy Harvesting in the Acidic Sweat Environment. Commun. 2020, 56 (13), 2004–2007. https://doi.org/10.1039/C9CC09533K.
  23. Park, J.; Sempionatto*, J. R.; Kim, J.; Jeong, Y.; Gu, J.; Wang, J.; Park, I. Microscale Biosensor Array Based on Flexible Polymeric Platform toward Lab-on-a-Needle: Real-Time Multiparameter Biomedical Assays on Curved Needle Surfaces. ACS Sensors 2020. https://doi.org/10.1021/acssensors.0c00078.
  24. Mishra, R. K.; Sempionatto*, J. R.; Li, Z.; Brown, C.; Galdino, N. M.; Shah, R.; Liu, S.; Hubble, L. J.; Bagot, K.; Tapert, S.; et al. Simultaneous Detection of Salivary Δ9-Tetrahydrocannabinol and Alcohol Using a Wearable Electrochemical Ring Sensor. Talanta 2020, 211, 120757. https://doi.org/10.1016/j.talanta.2020.120757.
  25. Jeerapan, Itthipon, Juliane R. Sempionatto, and Joseph Wang. “On‐body bioelectronics: wearable biofuel cells for bioenergy harvesting and self‐powered biosensing.” Advanced Functional Materials, 29 (2020): 1906243. https://doi.org/10.1002/adfm.201906243
  26. Sempionatto, Juliane R., Ahmed A. Khorshed, Aftab Ahmed, Andre N. De Loyola e Silva, Abbas Barfidokht, Lu Yin, K. Yugender Goud et al. “Epidermal enzymatic biosensors for sweat vitamin C: Toward personalized nutrition.” ACS sensors, 6 (2020): 1804-1813. https://doi.org/10.1021/acssensors.0c00604
  27. García Carmona, L.; Martin, A.; Sempionatto, J. R.; Moreto, J. R.; González, M. C.; Wang, J.; Escarpa, A. Pacifier Biosensor: Towards Non-Invasive Saliva Biomarker Monitoring. Chem. 2019, acs.analchem.9b03379. https://doi.org/10.1021/acs.analchem.9b03379.
  28. Sempionatto, J. R.; Jeerapan, I.; Krishnan, S.; Wang, J. Wearable Chemical Sensors: Emerging Systems for On-Body Analytical Chemistry. Chem. 2019. https://doi.org/10.1021/acs.analchem.9b04668.
  29. Sempionatto, J. R.; Brazaca, L. C.; García-Carmona, L.; Bolat, G.; Campbell, A. S.; Martin, A.; Tang, G.; Shah, R.; Mishra, R. K.; Kim, J.; et al. Eyeglasses-Based Tear Biosensing System: Non-Invasive Detection of Alcohol, Vitamins and Glucose. Bioelectron. 2019, 137, 161–170. https://doi.org/10.1016/j.bios.2019.04.058.
  30. Sempionatto, J. R.; Martin, A.; García-Carmona, L.; Barfidokht, A.; Kurniawan, J. F.; Moreto, J. R.; Tang, G.; Shin, A.; Liu, X.; Escarpa, A.; et al. Skin-Worn Soft Microfluidic Potentiometric Detection System. Electroanalysis 2019. https://doi.org/10.1002/elan.201800414.
  31. Jeerapan, I.; Sempionatto*, J. R.; Wang, J. On-Body Bioelectronics: Wearable Biofuel Cells for Bioenergy Harvesting and Self-Powered Biosensing. Funct. Mater. 2019, 1906243, 1–18. https://doi.org/10.1002/adfm.201906243.
  32. Ruiz-Valdepeñas Montiel, V.; Sempionatto, J. R.; Campuzano, S.; Pingarrón, J. M.; Esteban Fernández de Ávila, B.; Wang, J. Direct Electrochemical Biosensing in Gastrointestinal Fluids. Bioanal. Chem. 2019. https://doi.org/10.1007/s00216-018-1528-2.
  33. Garcia-Carmona, Laura, Aida Martin, Juliane R. Sempionatto, Jose R. Moreto, Maria Cristina Gonzalez, Joseph Wang, and Alberto Escarpa. “Pacifier biosensor: toward noninvasive saliva biomarker monitoring.” Analytical chemistry,21 (2019): 13883-13891. https://doi.org/10.1021/acs.analchem.9b03379
  34. Sandrini, Regiani MLM, Juliane R. Sempionatto*, Germano Tremiliosi‐Filho, Enrique Herrero, Juan M. Feliu, Janaina Souza‐Garcia, and Camilo A. Angelucci. “Electrocatalytic oxidation of glycerol on platinum single crystals in alkaline media.” ChemElectroChem,16 (2019): 4238-4245. https://doi.org/10.1002/celc.201900311
  35. Sempionatto, Juliane R., Aida Martin, Laura García‐Carmona, Abbas Barfidokht, Jonas F. Kurniawan, Jose R. Moreto, Guangda Tang et al. “Skin‐worn soft microfluidic potentiometric detection system.” Electroanalysis 31, 2 (2019): 239-245. https://doi.org/10.1002/elan.201800414
  36. Kim, J.; Jeerapan, I.; Sempionatto*, J. R.; Barfidokht, A.; Mishra, R. K.; Campbell, A. S.; Hubble, L. J.; Wang, J. Wearable Bioelectronics: Enzyme-Based Body-Worn Electronic Devices. Chem. Res. 2018. https://doi.org/10.1021/acs.accounts.8b00451.
  37. Mishra, R. K.; Martín, A.; Nakagawa, T.; Barfidokht, A.; Lu, X.; Sempionatto, J. R.; Lyu, K. M.; Karajic, A.; Musameh, M. M.; Kyratzis, I. L.; et al. Detection of Vapor-Phase Organophosphate Threats Using Wearable Conformable Integrated Epidermal and Textile Wireless Biosensor Systems. Bioelectron. 2018, 101, 227–234. https://doi.org/10.1016/j.bios.2017.10.044.
  38. Mishra, R. K.; Barfidokht, A.; Karajic, A.; Sempionatto*, J. R.; Wang, J.; Wang, J. Wearable Potentiometric Tattoo Biosensor for On-Body Detection of G-Type Nerve Agents Simulants. Sensors Actuators, B Chem. 2018. https://doi.org/10.1016/j.snb.2018.07.001.
  39. Ruiz-Valdepenas Montiel, V.; Sempionatto, J. R.; Esteban-Fernández De Ávila, B.; Whitworth, A.; Campuzano, S.; Pingarrón, J. M.; Wang, J. Delayed Sensor Activation Based on Transient Coatings: Biofouling Protection in Complex Biofluids. Am. Chem. Soc. 2018. https://doi.org/10.1021/jacs.8b08894.
  40. Kim, J.; Sempionatto, J. R.; Imani, S.; Hartel, M. C.; Barfidokht, A.; Tang, G.; Campbell, A. S.; Mercier, P. P.; Wang, J. Simultaneous Monitoring of Sweat and Interstitial Fluid Using a Single Wearable Biosensor Platform. Sci. 2018, 5 (10), 1800880. https://doi.org/10.1002/advs.201800880.
  41. Jeerapan, I.; Sempionatto, J. R.; You, J. M.; Wang, J. Enzymatic Glucose/Oxygen Biofuel Cells: Use of Oxygen-Rich Cathodes for Operation under Severe Oxygen-Deficit Conditions. Bioelectron. 2018. https://doi.org/10.1016/j.bios.2018.09.063.
  42. Sandrini, Regiani MLM, Juliane Renata Sempionatto, Enrique Herrero, Juan M. Feliu, Janaina Souza-Garcia, and Camilo A. Angelucci. “Mechanistic aspects of glycerol electrooxidation on Pt (111) electrode in alkaline media.” Electrochemistry Communications 86 (2018): 149-152. https://doi.org/10.1016/j.elecom.2017.11.027
  43. Sempionatto, J. R.; Mishra, R. K.; Martín, A.; Tang, G.; Nakagawa, T.; Lu, X.; Campbell, A. S.; Lyu, K. M.; Wang, J. Wearable Ring-Based Sensing Platform for Detecting Chemical Threats. ACS Sensors 2017, 2 (10), 1531–1538. https://doi.org/10.1021/acssensors.7b00603.
  44. Sempionatto, J. R.; Nakagawa, T.; Pavinatto, A.; Mensah, S. T.; Imani, S.; Mercier, P.; Wang, J. Eyeglasses Based Wireless Electrolyte and Metabolite Sensor Platform. Lab Chip 2017, 17 (10), 1834–1842. https://doi.org/10.1039/c7lc00192d.
  45. Martín, A.; Kim, J.; Kurniawan, J. F.; Sempionatto*, J. R.; Moreto, J. R.; Tang, G.; Campbell, A. S.; Shin, A.; Lee, M. Y.; Liu, X.; et al. Epidermal Microfluidic Electrochemical Detection System: Enhanced Sweat Sampling and Metabolite Detection. ACS Sensors 2017, 2 (12), 1860–1868. https://doi.org/10.1021/acssensors.7b00729.
  46. Jeerapan, I.; Sempionatto, J. R.; Pavinatto, A.; You, J. M.; Wang, J. Stretchable Biofuel Cells as Wearable Textile-Based Self-Powered Sensors. Mater. Chem. A 2016, 4 (47), 18342–18353. https://doi.org/10.1039/C6TA08358G.
  47. Sempionatto, Juliane R., Maria Gamella, Nataliia Guz, José M. Pingarrón, Valber A. Pedrosa, Sergiy Minko, and Evgeny Katz. “Electrochemically Stimulated DNA Release from a Polymer‐Brush Modified Electrode.” Electroanalysis 27, 9 (2015): 2171-2179. https://doi.org/10.1002/elan.201500252
  48. Basso, Caroline Rodrigues, Juliane R. Sempionatto, Claudia C. Tozato, Gustavo C. Rocha, João Pessoa Araujo, and Valber A. Pedrosa. “Effects of protein a in detection of canine distemper virus through immunosensor construction.” IEEE Sensors Journal,. 8 (2015): 4677-4683. https://doi.org/10.1109/JSEN.2015.2426421
  49. Crulhas, Bruno P., Juliane R. Sempionatto, Murilo F. Cabral, Sergiy Minko, and Valber A. Pedrosa. “Stimuli‐Responsive Biointerface Based on Polymer Brushes for Glucose Detection.” Electroanalysis, 4 (2014): 815-822. https://doi.org/10.1002/elan.201400030
  50. Sempionatto, Juliane R., Lucas C. Recco, and Valber A. Pedrosa. “Polymer brush modified electrode with switchable selectivity triggered by pH changes enhanced by gold nanoparticles.” Journal of the Brazilian Chemical Society, 25 (2014): 453-459. https://doi.org/10.5935/0103-5053.20130298